产品货号：
Z11364
中文名称：
ATG16L1抗体
英文名称：
Anti-ATG16L1 Antibody
产品规格：
80μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ATG16L1 Antibody |
| 指标别名 | APG16 like 1;APG16L;ATG16L;ATG16L1;Autophagy related protein 16 1;FLJ00045;FLJ10035;FLJ10828;FLJ22677;IBD10;WDR30 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | IF,WB,IHC |
| 基因名称 | ATG16L1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This ATG16L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-190 amino acids from human ATG16L. |
| 计算分子量 | 68kDa |
| 成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
| 纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
| 保存条件 | Maintain refrigerated at 2～8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
| 背景资料 | Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells,it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation.Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure,which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole).The APG12-APG5-APG16L complex is esential for the elongation of autophagic isolation membranes.This complex initially associates in uniform distribution with small vesicle membranes.During membrane elongation,the complex partitions,with a great concentration building on the outer side of the isolation membrane.Upon completion of the formation of the autophagosome,the APG12-APG5-APG16L dissociates from the membrane. |
| Uniprot ID | Q676U5 |
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